Medial Patellofemoral Ligament Reconstruction in Children - a 2-8 Years Follow-up Study (MPFL)

Aarhus University Hospital

Status: Active, not recruiting

Conditions: Medial Patellofemoral Ligament Reconstruction; Medial Patellofemoral Dislocation

Treatments: Other: MPFL-reconstruction

Study type: Observational

Funder types: Other

Identifiers

NCT06257836

Danish EC: 1-10-72-299-21

Details and patient eligibility

About

The purpose of this project is to investigate the treatment outcome after MPFL reconstruction in children as a treatment for chronic patellar instability, where the superficial part of the quadriceps tendon is fixed to the femur with anchors.

The outcome will be compared with a healthy cohort matched on age and gender.

Full description

Lateral patella dislocation (PL) is defined as a total dislocation of the patella out of the trochlea.

In chronic patella instability, where the patella has been repeatedly dislocated, the treatment is most often surgical. The main ligamentous structure that stabilizes the patella against lateralization is the medial patello-femoral ligament (MPFL). The MPFL is a centimeter-thin ligamentous structure that runs from the upper medial patellar border to the medial femoral epicondyle. This ligament is torn in more than 90% of cases of PL and healing of the ligament is often insufficient, especially if there are predisposing factors in the knee joint such as dysplasia of the patello-femoral joint, high standing patella (patella alta) and hypermobility.

MPFL reconstruction (MPFL-r) can be performed with many different surgical techniques, but the basic principle is to use autologous tendon tissue to create a new MPFL by anchoring the new tendon tissue to the medial patellar border and the medial femoral epicondyle, while ensuring isometry of the reconstruction.

A number of different methods have been described for anchoring the new MPFL to the patella and femoral condyle.

The most commonly used type of graft for MPFL-r is the gracilis tendon, which is fixed with screws in the femur bone preceded by drilling a channel in the femoral condyle.

In non-grown patients, the growth zone of the distal femur is very close to the anatomical attachment of the MPFL. This poses a problem as a reaming that hits the growth zone carries a theoretical risk of compromising growth around the knee.

In addition, up to 50% of patients describe pain at 1 year after surgery if screw fixation is used in the medial femoral condyle.

A new MPFL-r method using a superficial portion of the quadriceps tendon fixed with an anchor provides a good 2-year result compared to gracilis tendon and screw fixation.

The effectiveness and long-term efficacy of MPFL surgery with the quadriceps tendon for children is not well described in the literature.

At the Department of Sports Traumatology in Aarhus, Denmark, the quadriceps technique has been used on non-adult patients since 2016.

In this study, the investigators want to include the 80 patients who have undergone this MPFL-r since 2016 with the quadriceps tendon technique and have a minimum of 2 years of follow-up. This patient group will compared to a healthy cohort matched on age and gender.

Enrollment: 160 estimated patients

Sex: All

Ages: 14 to 23 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria - Intervention group:

• MPFL-reconstruction with Quadriceps tendon graft
• Open physis at surgery date
• Minimum 2 years Follow up

Exclusion Criteria - Intervention group:

• More surgeries in index knee
• MPFL-r in opposite knee
• MPFL revision in index knee

Inclusion Criteria - Healthy group:

• No knee problems

Exclusion Criteria - Healthy group

• None
• No knee problems

Trial design

160 participants in 2 patient groups

MPFL reconstruction with quadriceps graft

Description:

Children with medial patellofemoral reconstruction operated with epiphyses sparing quadriceps technique from 2016-2022.

Treatment:

Other: MPFL-reconstruction

Healthy Cohort

Description:

A healthy cohort matched on age (+/- 2 years) and gender