Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis (MaSep)

Universitätsmedizin Mannheim

Status: Unknown

Conditions: Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT01535534

2011-384N-MA

Details and patient eligibility

About

During the past years many investigators have focused on the immunological changes in sepsis disease, and great attention has been paid to the development of practicable means of immunomonitoring. Little is known about diagnostic and prognostic vascular biomarkers during the time course of patients with sepsis.

Full description

Primary Outcome Measures:

New diagnostic and prognostic markers for septic patients

Estimated Enrollment: 300 patients Study Start Date: January 2012 Estimated Study Completion Date: open Estimated Primary Completion Date: open

Intervention Details:

Procedure: vein puncture comparison of different inflammatory markers in the blood of septic patients

Enrollment: 250 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• SIRS-Criteria
• Proven Infection
• One sepsis-induced organ-failure
• Adults < 18 years old

Exclusion criteria

• Anemia
• Pregnancy
• Blood donor in the last 3 month