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Medication Adherence in Kidney Transplant Patients: SystemCHANGE™ Results of the Turkish MAGIC Randomized Clinical Trial

D

Dokuz Eylül University (DEU)

Status

Completed

Conditions

Medication Adherence

Treatments

Other: Education
Behavioral: Behavioral: SystemCHANGE

Study type

Interventional

Funder types

Other

Identifiers

NCT06106854
218S720

Details and patient eligibility

About

The SystemCHANGETM intervention harnesses patients' established daily routines/habits, environment, and important others, as possible solutions that are reoccurring and thus reliable systems that could support medication taking to become a dependable routine/habit. The aim of this study was to evaluate the effect of a six-month SystemCHANGE™ intervention compared to a six-month attention-control education intervention on medication adherence in adult kidney transplant recipients.

Enrollment

42 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

The inclusion criteria were patients having only kidney transplantation, aged 18 years or older, taking only immunosuppressant therapy twice daily, not staying in hospital and not diagnosed with a disease shortening their life span. They also were required to own a telephone, use an electronic medication cap and bottle, understand and speak Turkish, and have approval from their nephrologist to participate in the study. They were also assessed in person for cognitive impairment using the Standardized Mini Mental Test. Those who received a 23 or higher score on the test were enrolled in the study sample.

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

42 participants in 2 patient groups, including a placebo group

Intervention
Experimental group
Treatment:
Behavioral: Behavioral: SystemCHANGE
Control
Placebo Comparator group
Treatment:
Other: Education

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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