Medication Review Improves Pain Management and Quality of Life in Chronic Pain

Polytechnic Institute of Porto

Status: Completed

Conditions: Chronic Pain

Treatments: Other: Usual Care; Other: Medication Review Type III

Study type: Interventional

Funder types: Other

Identifiers

NCT06997861

CE/2023/87

Details and patient eligibility

About

The goal of this parallel-group, single-blinded, randomized study is to conduct Medication Review (MR) Type III in chronic non-cancer pain patients to optimize drug therapy and measure it's influence on Pain Intensity and Quality of Life in the primary care setting. The study took place in Porto, Portugal with the collaboration of two Primary Care Units (USF Arca D'Água and USF Campanhã - Polo S. Roque da Lameira) under ACeS Porto Oriental, from where patients were recruited. The main question it aims to answer is:

• Does the implementation of pharmacist-led medication review benefit patients with chronic pain in the primary care setting?
• Researchers will compare with "Usual Care" (UC) patients which receives general advice on how to manage their pain and/or recommendations to take "over the counter" drugs, similar to community pharmacy visits, to see if there is a clinically significant difference in pain intensity and quality of life between the two groups of patients.
• Participants will be asked to attend face-to-face interviews once a month for 4 months with an expert in medication review, that evaluates their current medication and suggests an individualized care plan. These plans include measures aimed at physicians (e.g., medication adding; dose reduction) and participants (e.g., non-pharmacological measures; adherence to medication).

Enrollment: 20 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Non-cancer chronic pain (>3 months, any cause)
• Follow-up at one of the selected Primary Care Units
• Average weekly pain score ≥4 at the screening phase
• Ability to attend monthly in-person or video interviews

Exclusion criteria

• Pregnancy
• Breastfeeding
• Dementia
• Other mental illness impairing self-reporting

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Medication Review (MR)

Experimental group

Treatment:

Other: Medication Review Type III

Usual-Care (UC)

Active Comparator group

Treatment:

Other: Usual Care