Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Aerobic Exercise

Cairo University (CU)

Status: Enrolling

Conditions: Familial Mediterranean Fever; Non-Alcoholic Fatty Liver Disease

Treatments: Behavioral: diet restriction; Behavioral: exercise plus diet restriction

Study type: Interventional

Funder types: Other

Identifiers

NCT07130318

IRB00014233-34

Details and patient eligibility

About

Familial Mediterranean fever (FMF) affect liver and causes some dysfunctions including non-alcoholic fatty liver.. still exercise and diet limitation is the treatment for this case

Full description

Familial Mediterranean fever (FMF women with fatty liver) will be collected to be cateogarized to group I or group II. Every group OF FMF will contain 20 FMF women. Both groups will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. Group I will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)

Enrollment: 40 estimated patients

Sex: Female

Ages: 30 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• familial Mediterrean fever women
• obese women
• women who have fatty live (non alcoholic type)

Exclusion criteria

• cardiac patients
• respiratory disease
• renal disease
• cancer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

40 participants in 2 patient groups

group number 1

Experimental group

Description:

Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. also, this group, Group I, will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)

Treatment:

Behavioral: exercise plus diet restriction

group number 2

Active Comparator group

Description:

Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months.

Treatment:

Behavioral: diet restriction