Meibomian Gland Dysfunction Management

University of the Incarnate Word

Status: Active, not recruiting

Conditions: Meibomian Gland Dysfunction; Contact Lens Discomfort

Treatments: Device: BlephEx; Device: Manual debridement

Study type: Interventional

Funder types: Other

Identifiers

NCT03652337

18-04-003

Details and patient eligibility

About

The purpose of this study is to compare electronic debridement of the eyelid margin (BlephEx) to manual debridement of the eyelid margin as treatment options for patients intolerant to contact lens wear consequent to Meibomian gland dysfunction.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Habitual contact lens wearers whose contact lens wear time has reduced due to MGD will be preferentially considered for this study. Subjects who currently cannot wear contact lenses due to MGD may be considered on a case-by-case basis.

Exclusion criteria

• Subjects who are currently using any prescription ophthalmic medications (such as antibiotics, steroids and immunomodulatory drugs) will be excluded from participation.
• Subjects who have active ocular infections will be excluded from participation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

BlephEx

Experimental group

Description:

The subjects who are enrolled in this arm will undergo electronic lid margin debridement using the BlephEx instrument.

Treatment:

Device: BlephEx

Manual debridement

Experimental group

Description:

The subjects who are enrolled in this arm will undergo manual lid margin debridement using a stainless steel ophthalmic golf spud.

Treatment:

Device: Manual debridement