Melanoma Inhibitory Activity (MIA): A Serological Marker for Metastatic Uveal Melanoma

Ludwig Maximilian University of Munich

Status: Unknown

Conditions: Melanoma; Metastatic Disease; Radiotherapy

Treatments: Procedure: Treatment of metastatic disease

Study type: Observational

Funder types: Other

Identifiers

NCT00406900

MIA

Details and patient eligibility

About

Uveal Melanoma is the most common primary intraocular tumor in adults. Most tumors metastasize to the liver. So far no sensitive or specific serological tumor marker is routinely used. The marker "Melanoma inhibitory activity" is a promising marker. Study hypothesis is to detect metastatic lesions in an early stage. This would increase life expectance of our patients

Full description

Serum is taken from each melanoma patient at every follow up after signed concent. With ELISA the marker MIA is evaluated. An increase of MIA serum level will lead to search for metastasis by oncologists.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• uveal melanoma (With/without overt metastatic disease)