Memory During Inhalation Anesthesia Performed With or Without Bispectral Index (BIS) in Patients Undergoing Thyroidectomy

Catholic University of the Sacred Heart

Status: Unknown

Conditions: Thyroidectomy

Treatments: Drug: Inhaled anesthetics

Study type: Observational

Funder types: Other

Identifiers

NCT01146431

A/1051/2009

Details and patient eligibility

About

The purpose of this study is 1) to investigate whether the use of BIS as a guide to the administration of inhaled anesthetic (sevoflurane or desflurane) compared with the use of hemodynamic parameters (blood pressure and heart rate) would affect the occurrence of implicit memory and /or dreams recall and 2) to check whether the occurrence of implicit memory and/or dreams recall is related with MAC (Minimal Alveolar Concentration) of inhalational anesthetics and/or preoperative anxiety levels.

Enrollment: 130 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 18 and 70 years
• Class-ASA Physical Status I-II

Exclusion criteria

• Psychiatric or neurological disorders and/or hearing disorders
• Obesity (Body Mass Index > 30)
• Drug addiction, alcoholism
• Patient with difficulty in understanding italian language and/or education level below middle school

Trial design

130 participants in 2 patient groups

Hemodynamic parameters

Description:

Hemodynamic parameters will be used as a guide for anesthesia.

Treatment:

Drug: Inhaled anesthetics

Drug: Inhaled anesthetics

BIS

Description:

Bispectral Index (BIS) will be used as a guide for anesthesia.

Treatment:

Drug: Inhaled anesthetics

Drug: Inhaled anesthetics