Memory Encoding Strategies for People With Mild Cognitive Impairments

University of Western Sydney

Status: Completed

Conditions: Mild Dementia; Mild Cognitive Impairment

Treatments: Other: Behavioral: semantic-based memory encoding training; Other: Behavioral: perceptual-based memory encoding training; Other: Behavioral: Cognitive stimulation group (control group)

Study type: Interventional

Funder types: Other

Identifiers

NCT02953964

Memory encoding

Details and patient eligibility

About

The purposes of the study are:

• To evaluate the effectiveness of a perceptual-based training program in enhancing cognitive and everyday functioning of older adults with mild cognitive impairment and mild dementia
• To evaluate the effectiveness of a semantic-based training program in enhancing cognitive and everyday functioning of older adults with mild cognitive impairment and mild dementia

Full description

People with dementia experience a cognitive decline that affects their functional performance. It has been identified that encoding is less effective in people with dementia. Rehabilitating at the encoding stage is, therefore, essential. A recent systematic review found that effective interventions needed to include training in individually selected memory encoding strategies. These strategies are classified as either perceptual (visual) or semantic (association) memory encoding strategies.

Based on the above literature, the chief investigator (Associate Professor Karen Liu) ran a pilot study on an integrated home and community centre cognitive training programme for 20 elderly people with memory problem using a pre-test and post-test comparison design.

Extending on the positive results, the aim of this project was to investigate the effectiveness of perceptual and semantic encoding strategies (and compare with a control intervention). It also aims to promote the understanding of memory loss and dementia and the need for early intervention for family members of the participants.

Enrollment: 60 patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Selection Criteria:

• are aged 60 or above;
• have no previous psychiatric or memory disorder history or other neurological illness;
• have Mini-mental State Examination score (MMSE) greater than or equal to 21;
• have Clinical Dementia Rating score (CDR) of 0.5 or 1 indicating very mild and mild dementia;
• do not show sign of depression with score below 9 out of 30 in the Geriatric Depression Scale;
• are able to communicate effectively;
• have family member who can participate in the study; and
• voluntarily consent to participate in the study.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

60 participants in 3 patient groups

Behavioral: perceptual-based memory encoding training

Experimental group

Description:

Participants receive perceptual-based memory encoding training

Treatment:

Other: Behavioral: perceptual-based memory encoding training

Behavioral: Semantic-based memory encoding training

Experimental group

Description:

Participants receive semantic-based memory encoding training

Treatment:

Other: Behavioral: semantic-based memory encoding training

Behavioral : control group

Active Comparator group

Description:

Participants receive cognitive stimulation intervention

Treatment:

Other: Behavioral: Cognitive stimulation group (control group)