Meningioma and Embolism Thrombosis Risk & Investigation of Coagulation (001_2024_BO2)

University Hospital Tuebingen

Status: Enrolling

Conditions: Surgical Resection; Meningeoma; Thrombembolism

Study type: Observational

Funder types: Other

Identifiers

NCT06709833

001_2024_BO2

Details and patient eligibility

About

Despite being generally benign tumors, meningiomas are associated with an increased risk for thrombembolic complications after surgical resection. The molecular mechanisms underlying this circumstance are still unknown.

In this prospective observational trial, the investigators aim to evaluate the changes in coagulation and platelet function caused by tumor resection.

Blood samples are obtained by patients undergoing meningioma resection before and immediately after resection to detect said changes.

As a control cohort, blood samples are obtained from patients undergoing resection for glioma.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients undergoing resection for meningioma or
• Patients undergoing resection for glioma or
• Healthy controls
• written consent for study participation

Exclusion criteria

Trial design

100 participants in 3 patient groups

Meningioma resection

Description:

patients undergoing resection for meningioma

Glioma resection

Description:

Patients undergoing glioma resection as a control cohort for meningioma patients

Healthy controls

Description:

Healthy controls without tumor and surgical resection