Mental Health Associations With Vitiligo

Momentum Data

Status: Completed

Conditions: Adjustment Disorders; Social Phobia; Suicide, Attempted; Vitiligo; Parasuicide; Overdose; Depressive Episode; Recurrent Depressive Disorder; Substance Abuse; Anxiety Disorders; Self-Harm, Deliberate

Treatments: Other: Exposure of mental health condtion of interest

Study type: Observational

Funder types: Industry

Identifiers

NCT04953338

P044

Details and patient eligibility

About

This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with vitiligo compared to controls and to evaluate whether the relative risks may vary by different ethnicity.

Full description

This study has two primary outcomes 1) Prevalence and incidence of mental health condtions in people diagnosed with vitiligo compared to matched controls and 2) Primary care and secondary healthcare utilisation in patients diagnosed with vitiligo and having a prevalent depressive conditon compared to matched controls. In addition, the study examines risk of time off work and unemployment in people diagnosed with vitiligo compared to matched controls.

Enrollment: 36,104 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All eligible adults ≥18 (as at date of vitiligo diagnosis for cases or start of follow-up for controls) registered with GP practices contributing data to OPCRD between January 1, 2004 and December 31, 2020, were eligible for inclusion in the study.

Exclusion criteria

• People with less than 1 year of follow up available

Trial design

36,104 participants in 2 patient groups

Cases

Description:

Patients with a confirmed diagnosis of Vitiligo within the study period will be included as cases for analysis.

Treatment:

Other: Exposure of mental health condtion of interest

Controls

Description:

The controls will be defined by matching cases with people who have never been diagnosed with vitiligo either prior to or during the study period, by age and sex, at General Practice level.

Treatment:

Other: Exposure of mental health condtion of interest