Mentalization - Based Treatment: Adolescents With Co-morbid Depression and Personality Disorder (MBT)

North East London Foundation Trust

Status: Unknown

Conditions: Personality Disorder; Depression

Treatments: Other: treatment as usual; Other: MBT

Study type: Interventional

Funder types: Other

Identifiers

NCT01204346

TRossouw

Details and patient eligibility

About

Mentalisation based treatment (MBT) for young people with co-morbid depression and emerging personality disorder will be more effective in a day/inpatient setting than treatment as usual.

Full description

Systematic literature review on outcomes with young people with depression and emerging personality disorder showed clear evidence that this group of young people are severely hampered and adult outcomes are strongly linked to both adult PD as well as adult psychiatric disturbance and lower levels of adult functioning. (Crawford et al, 2008; Kasen et al, 1999; Kasen et al, 2007; Lewinsohn et al, 1999) This argues very clearly for the need to diagnose young people presenting with co-morbid depression and emerging personality disorder in order to intervene and help these young people's struggles as it will prevent poor prognostic adult outcomes. There were no treatment programs that specifically focussed on the treatment of this co-morbid group in the literature. Several studies focussed on the treatment of depression alone and only one RCT focussed on the treatment of adolescent personality disorder (Chanen et al, 2007). In adult studies mentalization-based treatment programs were found to be effective ( as well as cost effective) in a day hospital setting for adults with personality disorder and depression (Bateman, et al, 2007) This study aims to conduct a control trial to test whether MBT will be more effective than TAU in this group. All cases will be tested on admission, at discharge and followed up at 2 years post discharge.

Enrollment: 75 estimated patients

Sex: All

Ages: 12 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all young people who are admitted to Brookside adolescent unit between the ages 12 - 17 presenting with depression and emerging personality disorder will be eligible

Exclusion criteria

• Young people with autistic spectrum disorders or severe learning disabilities.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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75 participants in 2 patient groups

MBT group

Experimental group

Description:

mentalization based treatment program

Treatment:

Other: MBT

Treatment as usual group

Active Comparator group

Description:

treatment as usual group

Treatment:

Other: treatment as usual