Meta-analysis of Efficacy of Topotecan

GlaxoSmithKline (GSK)

Status: Completed

Conditions: Cervical Intraepithelial Neoplasia

Treatments: Drug: topotecan; Drug: cisplatin; Drug: paclitaxel

Study type: Observational

Funder types: Industry

Identifiers

NCT01160185

114015

Details and patient eligibility

About

This meta-analysis was conducted to investigate the efficacy of Topotecan and other treatments for recurrent and stage IVB carcinoma of the cervix

Full description

Studies included in the meta-analysis were: GOG-0179, GOG-0204 & GOG-0169

Enrollment: 1 patient

Sex: Female

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Randomised Clinical Trials or systematic reviews or meta-analyses
• Treatment with topotecan or platinum-based single and combination regimens in female patients of any race with cancer of the cervix recurrent after radiotherapy or stage IVB disease

Exclusion criteria

• None

Trial design

1 participants in 3 patient groups

cisplatin

Treatment:

Drug: cisplatin

cisplatin + topotecan

Treatment:

Drug: topotecan

Drug: cisplatin

cisplatin + paclitaxel

Treatment:

Drug: paclitaxel

Drug: cisplatin