Meta-analysis of Stannous Fluoride and the Effects on Dental Plaque

Procter & Gamble (P&G)

Status: Completed

Conditions: Dental Plaque

Treatments: Drug: Positive control dentifrice; Drug: Stannous fluoride dentifrice; Drug: Negative control dentifrice

Study type: Observational

Funder types: Industry

Identifiers

NCT04006483

2019SnF2PlaqueAnalysis

Details and patient eligibility

About

The aim of this 18 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices when used up to 3 months on dental plaque relative to a positive or negative control dentifrice.

Enrollment: 2,359 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Subjects were excluded from this study for the following reasons;

• pregnancy,
• rampant caries,
• severe periodontitis,
• at discretionary of the Principal Investigator.

Trial design

2,359 participants in 3 patient groups

Stannous Fluoride Dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Stannous fluoride dentifrice

Positive control dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Positive control dentifrice

Negative control dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Negative control dentifrice