Meta-analysis of Stannous Fluoride and the Effects on Gingival Health

Procter & Gamble (P&G)

Status: Completed

Conditions: Gingivitis

Treatments: Drug: Negative control dentifrice; Drug: Stannous Fluoride Dentifrice; Drug: Positive control dentifrice

Study type: Observational

Funder types: Industry

Identifiers

NCT03970759

2019SnF2GIAnalysis

Details and patient eligibility

About

The aim of this 18 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices when used up to 3 months on gingivitis relative to a positive or negative control dentifrice.

Enrollment: 2,890 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Subjects were excluded from this study for the following reasons;

• pregnancy,
• rampant caries,
• severe periodontitis,
• at discretionary of the Principal Investigator.

Trial design

2,890 participants in 3 patient groups

Stannous Fluoride Dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Stannous Fluoride Dentifrice

Positive Control Dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Positive control dentifrice

Negative Control Dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Negative control dentifrice