Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity

Procter & Gamble (P&G)

Status: Completed

Conditions: Dentine Hypersensitivity

Treatments: Drug: Negative control dentifrice; Drug: Positive control dentifrice; Drug: Stannous fluoride dentifrice

Study type: Observational

Funder types: Industry

Identifiers

NCT04005417

2019SnF2SensitivityAnalysis

Details and patient eligibility

About

The aim of this 11 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) on dentine hypersensitivity versus a positive or negative control dentifrice.

Enrollment: 1,036 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Subjects were excluded from this study for the following reasons;

• severe periodontitis
• at discretionary of the Principal Investigator

Trial design

1,036 participants in 3 patient groups

Stannous fluoride dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Stannous fluoride dentifrice

Positive control dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Positive control dentifrice

Negative control dentifrice

Description:

Twice daily brushing

Treatment:

Drug: Negative control dentifrice