Metabolic Availability of Lysine From Rice

The Hospital for Sick Children

Status and phase: Completed; Phase 1

Conditions: Healthy Adults

Treatments: Dietary Supplement: Amino Acid Crystalline Lysine Amino Acid Mix; Dietary Supplement: Cooked Rice containing Lysine

Study type: Interventional

Funder types: Other

Identifiers

NCT01474226

0019850580

CIHR, grant MT10321 (Other Grant/Funding Number)

Details and patient eligibility

About

The purpose of this study is to investigate the digestibility of the amino acid lysine in cooked rice in adult men using stable isotope technique.

Full description

The investigators objective is to determine the metabolic availability (MA) of lysine in cooked white rice protein using the indicator amino acid oxidation (IAAO) technique. Five men will receive graded levels (20, 40, and 60, and 70%) of the lysine requirement of 35 mg/kg/d as a crystalline AA mixture,and cooked rice protein (20, 40 and 60%), respectively.

Enrollment: 5 patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy Adult males (18 to 50years old)

Exclusion criteria

• A history of recent weight loss or illness
• Use of any medication at the time of entry into the study.

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

Lysine Amino Acid

Experimental group

Treatment:

Dietary Supplement: Cooked Rice containing Lysine

Dietary Supplement: Amino Acid Crystalline Lysine Amino Acid Mix