Metabolic Characteristics of Plasma OxPLs in STEMI Patients.

First Affiliated Hospital of Ningbo University

Status

Invitation-only

Conditions

STEMI - ST-segment Elevation Myocardial Infarction

Study type

Observational

Funder types

NETWORK

Identifiers

NCT07382700

2025004A

Details and patient eligibility

About

The goal of this observational study is to investigate the structural composition and metabolic characteristics of OxPLs in STEMI patients. Explore OxPLs characteristic fingerprint biomarkers from different populations and analyze OxPLs fingerprint spectra. Based on the OxPLs fingerprint of STEMI patients, a machine learning classifier is used to establish an artificial intelligence assisted post PCI MACE risk prediction system, achieving the transformation of basic research into clinical application.

Enrollment

240 estimated patients

Sex

All

Ages

50 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

The patient meets the diagnostic criteria for STEMI (refer to the "Diagnosis and Treatment Guidelines for Acute ST Segment Elevation Myocardial Infarction (2021)")
Agree to perform direct PCI
The onset time is less than 12 hours and successfully undergoing emergency PCI treatment
After admission, all STEMI patients are routinely treated with antiplatelet aggregation, anticoagulation, lipid-lowering, and anti myocardial remodeling drugs.

Exclusion criteria

Previous history of myocardial infarction
Accompanied by other cardiovascular diseases, such as severe heart valve disease, severe heart failure, congenital heart disease, cardiomyopathy, etc
Merge with severe infection
Merge with severe anemia
Merge with severe liver and kidney dysfunction
Combined with malignant tumors
Accompanied by a history of autoimmune or hematological diseases
Recent history of severe trauma or surgery
Patients with incomplete clinical data
The patient does not agree to undergo data collection