Metabolic Effects of High-amylose Wheat-based Rusks.

Federico II University

Status: Completed

Conditions: Hyperglycemia

Treatments: Other: Test meal

Study type: Interventional

Funder types: Other

Identifiers

NCT02702934

233/14

Details and patient eligibility

About

Amylose-amylopectin ratio may influence the rate of starch digestion. This randomized controlled study evaluated the postprandial metabolic effects of amylose-rich- wheat- based rusks in overweight subjects.

Enrollment: 10 patients

Sex: All

Ages: 30 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Overweight/obese;
• 30-60 years.

Exclusion criteria

• age <30 and >60 years;
• fasting triglycerides ≥400 mg/dl;
• fasting cholesterol >270 mg/dl;
• cardiovascular events (myocardial infarction or stroke) during the 6 months prior to the study;
• established diabetes mellitus or any chronic disease;
• renal and liver failure (creatinine >1.7 mg/dl and transaminases >2 times than normal values, respectively);
• anaemia (Hb <12 g /dl);
• any chronic disease.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

---

10 participants in 2 patient groups

High-amylose rusks

Experimental group

Description:

Test meal with 100g of carbohydrates coming from high-amylose rusks

Treatment:

Other: Test meal

Control rusks

Active Comparator group

Description:

Test meal with 100g of carbohydrates coming from regular rusks used as control

Treatment:

Other: Test meal