Metabolic Effects of Olanzapine in Healthy Males

University at Buffalo (UB)

Status: Completed

Conditions: Healthy

Treatments: Drug: Placebo; Drug: Olanzapine

Study type: Interventional

Funder types: Other

Identifiers

NCT01496183

PCH0320106A

Details and patient eligibility

About

The purpose of this study is to look at how a two-week use of a medication called Olanzapine might change appetite, physical activity, resting metabolic rate, body composition, and weight in healthy men.

Enrollment: 24 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy Volunteer
• Male
• Aged 18-35 years
• Body Mass Index (BMI): <30 kg/m2

Exclusion criteria

• Presence of any medical disorder that may confound the assessment of relevant biological measures

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

24 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Treatment:

Drug: Placebo

Olanzapine

Experimental group

Treatment:

Drug: Olanzapine