Metabolic Effects of One-weak Heavy Drinking (ROSMET)

University Hospital, Gentofte, Copenhagen

Status

Completed

Conditions

Alcohol; Harmful Use

Metabolic Disturbance

Glucose Intolerance

Treatments

Behavioral: Festival participation

Study type

Interventional

Funder types

Other

Identifiers

NCT04229550

H-15019685

Details and patient eligibility

About

Examination of the effect of one week's unhealthy lifestyle on glucose metabolism and liver parameters in a group of young, healthy males participating in Roskilde Festival 2016.

Full description

Metabolic effects of intermittent unhealthy lifestyle in otherwise young healthy adults are poorly studied. The investigators evaluated the effect of one week's unhealthy lifestyle on glucose metabolism and liver parameters in a group of young, healthy males participating in Roskilde Festival 2016.

Festival participants were studied before and after participation (one week) in Roskilde Festival 2016 and matched with controls who lead a normal life for an equivalent period of time. An oral glucose tolerance test (OGTT), abdominal ultrasound and strain elastography for liver stiffness were performed together with a bioimpedance scan and cognitive tests.

Enrollment

28 patients

Sex

Male

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

BMI of 18,5-25 kg/m2
Normal liver function (assessed by ASAT, ALAT, GGT, alkaline phosphatase, albumin and bilirubin, coagulation factors II, VII and X, INR and platelets)

Exclusion criteria

Planning alcohol withdrawal or dieting/a special low-fat diet during Roskilde Festival
Diabetes or pre-diabetes
First degree relatives with diabetes
Kidney disease (eGFT<60 ml/min and/or albuminuria)
Chronic diseases (in addition to those already mentioned) that could affect participation in festival activities (concerts and parties)
Any condition in which the investigator believed would make it impossible to participate