Metabolic Effects of Plant-based Diet

Koç University

Status: Completed

Conditions: Fatty Liver; Healthy Lifestyle; Healthy Nutrition; Insulin Resistance; Healthy Diet; Metabolic Syndrome

Treatments: Dietary Supplement: Vegetarian; Dietary Supplement: Vegan; Dietary Supplement: Omnivore

Study type: Interventional

Funder types: Other

Identifiers

NCT05351853

28041993

Details and patient eligibility

About

The purpose of this study is to assess the metabolic effects of plant based diet on healthy young adults.

Full description

An internet announcement will be made and 60 participants who meet the eligibility requirements will be randomly selected. After being informed about study, all participants (60 omnivores) giving written informed consent will be assigned to the vegan and vegetarian groups of the study according to their preferences, while 20 participants will continue to be omnivores as the control group. At week 0 and 24, blood samples, urine samples, proton density fat fraction MRI evaluations and body composition analyze will be completed.

Enrollment: 60 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Being 18-40 years old,
2. BMI is 18-30 kg/m2,
3. Having no chronic diseases,
4. Not smoking

Exclusion criteria

1. Having chronic disease,
2. Being older than 40 years old or younger than 18 years old,
3. Smoking,
4. Alcoholism or drinking more than 140 gr/week of alcohol,

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 3 patient groups

Control Group

Other group

Description:

20 healthy individual will be in the control group. Participants of control group will not change their diet and will continue omnivore diet.

Treatment:

Dietary Supplement: Omnivore

Vegetarian

Other group

Description:

20 healthy individual will be in the control group. Participants of this group will change their diet from omnivore to vegetarian (no meat /meat products) after the beginning of the study.

Treatment:

Dietary Supplement: Vegetarian

Vegan

Other group

Description:

20 healthy individual will be in the control group. Participants of this group will change their diet from omnivore to vegan (%100 plant based) after the beginning of the study.

Treatment:

Dietary Supplement: Vegan