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Metabolic Effects of Treatment of Chronic Periodontitis in Non-diabetic Subjects (PARODIA2)

Y

Yaounde Central Hospital

Status

Completed

Conditions

Prediabetes
Periodontitis

Treatments

Procedure: non-surgical periodontal treatment

Study type

Interventional

Funder types

Other

Identifiers

NCT02830113
CNO20155

Details and patient eligibility

About

This study was aimed at assessing the effects of non-surgical periodontal treatment (NSPT) of chronic periodontitis on insulin sensitivity, glucose tolerance, and serum C-reactive protein(CRP) level amongst non-diabetic subjects.

Full description

Subjects with chronic periodontitis will undergo non-surgical periodontal treatment (NSPT) consisting of a complete scaling, polishing, root planning, and the irrigation of periodontal pockets with a 10% povidone iodine solution. Periodontal parameters (plaque index, gingival bleeding index, pocket depth, and clinical attachment loss), insulin sensitivity using KITT, glucose tolerance using oral glucose tolerance test and serum CRP level by immunoturbidimetry will be measured before and 3 months after the NSPT.

Enrollment

20 patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Chronic periodontitis
  • Non diabetic individual

Exclusion criteria

  • Known diabetes
  • Periodontal treatment less than 6 months prior to inclusion
  • Having less than 20 natural teeth

Trial design

Primary purpose

Prevention

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

20 participants in 1 patient group

non-surgical periodontal treatment
Experimental group
Description:
One session of non-surgical periodontal treatment consisting of a complete scaling, polishing, root planning, and the irrigation of periodontal pockets with a 10% povidone iodine solution.
Treatment:
Procedure: non-surgical periodontal treatment

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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