Metabolic Exercise Testing (RANNOU)

Regional University Hospital Center (CHRU)

Status: Enrolling

Conditions: Myalgia; Exercise Test; Metabolic Myopathies

Treatments: Genetic: matching genotype with phenotype; Device: functional test

Study type: Observational

Funder types: Other

Identifiers

NCT02362685

RANNOU

Details and patient eligibility

About

Exertional symptoms are the hallmarks of metabolic myopathies, supporting the concept of using functional tests when this diagnosis is suspected. Exercise increases the concentration of muscle metabolites in the venous blood supply (e.g. lactate, pyruvate, and ammonia) especially during recovery. The purpose of this study is to compare the results of exercise testing with to the data from muscle biopsy or genetic analysis.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 5+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Referred to the Physiology Department of Brest Hospital for a metabolic exercise test
• Ability to provide informed consent

Exclusion criteria

• Contraindication(s) to perform cardiopulmonary exercise testing (ATS/ACCP statement on cardiopulmonary exercise testing, Am J respi Care Med 167: 211-77, 2003)
• Pregnancy or unknown pregnancy status.

Trial design

1,000 participants in 1 patient group

metabolic exercise testing

Description:

All the subjects referred to performed a metabolic exercise testing.

Treatment:

Genetic: matching genotype with phenotype

Device: functional test