Metabolic Features Effects on FAST Score in MASLD Patients

Tanta University

Status

Enrolling

Conditions

Metabolic Dysfunction-Associated Steatotic Liver Disease

Treatments

Radiation: Transient Elastography

Study type

Observational

Funder types

Other

Identifiers

NCT06867419

36264PR889/10/24

Details and patient eligibility

About

The goal of this observational cross-sectional study is to evaluate the effect of metabolic features on Fibroscan-AST (FAST) score stratification in metabolic dysfunction-associated steatotic liver disease (MASLD) patients in Egypt.

Researchers will identify the metabolic risk factors in patients with MASLD. evaluate the effect of metabolic features on stratifying MASLD patients by predicting higher FAST score.

Participants will be subjected to history taking, clinical examination, laboratory investigations, abdominal ultrasonography, and transient elastography (Fibroscan) to measure liver stiffness (LSM) and controlled attenuation parameter (CAP). The Non-alcoholic fatty liver disease (NAFLD) fibrosis score and FAST score will be calculated.

Enrollment

385 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All patients with MASLD who had steatosis detected by (VCTE-CAP) elastography

Exclusion criteria

Patients with a history of significant alcohol consumption more than 30 g/day in men and > 20 g/day in women.
Patients with positive hepatitis B or C virus markers.
Patients with autoimmune hepatitis.
Patients with any other metabolic liver disease.
Patients with hepatic focal lesions.