Metabolic Profile of Users of Hormonal and Non-hormonal Contraceptives

Federal University of São Paulo

Status: Completed

Conditions: Contraceptive Usage; Body Weight Changes; Metabolic Syndrome

Treatments: Drug: Combined Oral Contraceptive; Device: Intrauterine device; Drug: Depot-Medroxyprogestereone Acetate; Drug: Progestin-only pills

Study type: Observational

Funder types: Other

Identifiers

NCT03383185

CAAE: 45523715.4.0000.5505

Details and patient eligibility

About

Evaluation of metabolic profile of users of hormonal and non-hormonal contraceptives during five years follow-up

Full description

Were eligible for the study 489 Women, followed in Federal University of São Paulo Family Planning Service, who used the same contraceptive method during five year of follow-up, According to the service protocol, the patients, after had participated of a orientation group about contraceptives methods, elected one of them. After that, if the choice had been according to the eligibility criteria of World Health Organization, it was approved by a gynecologist.

The contraceptive methods available were the intrauterine device (IUD) oral contraceptives, including combined pills and progestin-only formulations, and depot medroxyprogestereone acetate.

The study consisted in the evaluation of their medical records of weight, BMI, Blood pressure, glycemia, seric levels of cholesterol and triglycerides, during the five years, and in the comparison of the differences of these data between the contraceptive methods.

Enrollment: 489 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• women in reproductive age followed in Federal university of Sao Paulo Family Planning Service
• use of the same contraceptive method during five years

Exclusion criteria

• incomplete data

Trial design

489 participants in 2 patient groups

Non-hormonal contraceptive

Description:

Users of non- hormonal intrauterine device during the 5 years follow-up

Treatment:

Device: Intrauterine device

Hormonal contraceptives

Description:

Users of combined oral contraceptive, progestin-only pills, depot-medroxyprogestereone acetate during 5 years follow-up

Treatment:

Drug: Combined Oral Contraceptive

Drug: Depot-Medroxyprogestereone Acetate

Drug: Progestin-only pills