Metabolic Risk Following Gestational Diabetes Mellitus (IMAGE)

Civil Hospices of Lyon

Status

Completed

Conditions

Gestational Diabetes

Treatments

Other: Blood sampling and OGTT

Study type

Interventional

Funder types

Other

Identifiers

NCT02133729

2010.649

Details and patient eligibility

About

Gestational diabetes (GDM) is defined by abnormal glucose tolerance during gestation. This complication occurs in 4-10% and is associated with fetal complications and macrosomia. In addition, women with GDM have an increased risk to develop type 2 diabetes after delivery. Despite recommendations, it is difficult to follow-up all women with GDM during the postpartum period due to high numbers of subjects that exceed usual healthcare resources. It is therefore necessary to focus clinical attention toward women at high risk of type 2 diabetes in order to set adequate preventive strategies.

Enrollment

255 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Women aged over 18years old
Women with the criteria of GDM during pregnancy at 21-35 weeks of gestation (one situation):
- After a 75g Oral Glucose Tolerance Test (OGTT - WHO criteria) with blood glucose (BG) values at T60≥180mg/dl and/or T120≥153mg/dl
- An O. Sullivan test following a 100g oral glucose load with at least two pathological values (T60 ≥ 180mg/dl and/or T120 ≥ 155mg/dl and/or T180 ≥ 140mg/dl)
- With a fasting BG value ≥92mg/dl
Women with signed informed consent

Exclusion criteria

Women aged less than 18years old
Women with pregestational type 2 diabetes
Women without signed informed consent
Women who does not read and/or understand french language
Women not affiliated to the health care system
Women with recent infection (<1month) and/or on steroids or anti-inflammatory drugs.
Women with chronic diseases
Women with a disable state
Women with normal glucose tolerance
Women already incorporated in another clinical study that could interfere with the present study