Metabolic Syndrome and Contrast Induced Nephropathy

Ankara University

Status: Completed

Conditions: Contrast Induced Nephropathy; Metabolic Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT02192372

MetS CIN

Details and patient eligibility

About

Prevention of contrast induced nephropathy after interventional cardiologic procedures deserves close interest because of its association with prolonged hospitalization, increased cost and increased in hospital and long term mortality rates. An observational prospective cohort study was designed to determine whether metabolic syndrome predicts the development of contrast induced nephropathy after elective percutaneous coronary intervention.

Enrollment: 599 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients must be scheduled for elective percutaneous coronary intervention Clinical diagnosis of metabolic syndrome Patients must give informed consent

Exclusion criteria

Acute coronary events Acute renal failure End stage renal failure requiring hemodialysis Contrast allergy and exposure to nephrotoxic agent within 1 week before percutaneous coronary intervention Exposure to contrast agent within 1 week before the procedure.

Trial design

599 participants in 2 patient groups

metabolic syndrome

Description:

Presence of 3 or more of these components: high fasting glucose (fasting serum glucose ≥ 100 mg/dl or drug treatment for elevated blood glucose), abdominal obesity (given as waist circumference \> 102 cm in men and \> 88 cm in women), high blood pressure (≥130/≥85 mmHg or drug treatment for hypertension), hypertriglyceridemia (serum triglycerides ≥150 mg/dl), low high-density lipoprotein cholesterol (\<40 mg/dl in men and \<50 mg/dl in women).

control

Description:

Age and sex adjusted control subjects