Metabolic Syndrome and Female Breast Cancer

Catholic University of Pelotas

Status

Completed

Conditions

Breast Cancer

Treatments

Other: Observation about the presence of metabolic syndrome

Study type

Observational

Funder types

Other

Identifiers

NCT02282592

481.165

Details and patient eligibility

About

The role among metabolic syndrome and breast cancer risk is not well understood and must be further explored. The objective of this study is to evaluate the association between metabolic syndrome and breast cancer in Southern Brazil. In this case-control study, breast cancer patients and controls without malignant disease, matched for age (±5 years) and menopausal status, were interviewed and asked to make a glucose, HDL-cholesterol and triglycerides test. Waist circumference and blood pressure were measured using standardized procedures. Metabolic Syndrome was considered by NCEP ATP III (2001) and IDF (2006) definitions. Cases and controls were compared in relation to the presence of diagnosed MetS (yes/no), number of metabolic abnormalities identified (1 to 5) for each definition, and according to each metabolic abnormality cutoff point.

Enrollment

164 patients

Sex

Female

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

For cases: having newly diagnosed breast cancer without adjuvant or neoadjuvant treatment;
For controls: having no evidence of cancer; be matched for age and menopausal status with controls

Exclusion criteria

Women with a recidivated tumor, HIV infection, renal, heart or liver disease, hypothyroidism or hyperthyroidism, mobility or neurological limitations, chronicle use of corticosteroids, pacemakers or identified with severe edema were excluded.