Metabolic Syndrome in Patients Undergoing Endovascular Aortic Repair (EVAR)

University of Thessaly

Status: Unknown

Conditions: Endovascular Aortic Repair; Metabolic Syndrome

Treatments: Other: EVAR

Study type: Observational

Funder types: Other

Identifiers

NCT04152395

Metabolic syndrome in EVAR

Details and patient eligibility

About

This prospective study aims to identify the prevalence of metabolic syndrome in patients undergoing EVAR and the implications of metabolic syndrome on the postoperative outcome, the major complications, the thromboembolic events and the perioperative mortality and morbidity of the patients undergoing vascular surgery.

Full description

Patients scheduled for elective EVAR will be randomly divided in two groups. One group patients with metabolic syndrome and one without.

Metabolic syndrome is defined by the definition of 2009 as:

Increased waist circumflex (>94 cm in men and > 80 cm in women), increased triglycerides or in therapy, decreased HDL (< 40 mg/dl in men and <50mg/dl in women) or in therapy, Increased blood pressure (Systolic Blood Pressure>130 mmHg or Diastolic Blood Pressure>85 mmHg) or in therapy, increased fasting glucose (>100mg/dl) or in therapy.

All the patients will be monitored throughout the perioperative period, at 30 days, 6 and 12 months, and any major or minor complication will be recorded.

Enrollment: 220 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• elective EVAR

Exclusion criteria

• Patients incapable to give informed consent
• Pregnancy
• Cancer
• Systematic Inflammatory disease
• Use of steroids
• Emergency surgery
• Prior ICU admission

Trial design

220 participants in 2 patient groups

Metabolic group

Description:

Patients with metabolic syndrome undergoing EVAR

Treatment:

Other: EVAR

Control group

Description:

Patients without metabolic syndrome undergoing EVAR

Treatment:

Other: EVAR