Metacognitive Therapy Compared to Cognitive-behavioral Therapy

Karolinska Institute

Status: Not yet enrolling

Conditions: Posttraumatic Stress Disorder (PTSD); Generalized Anxiety Disorder; Social Anxiety Disorder

Treatments: Behavioral: Disorder-specific cognitive-behavioral therapy; Behavioral: Transdiagnostic metacognitive therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT07382323

KI-2025-07875-02

Details and patient eligibility

About

This is a qualitative study of participants who have taken part in a randomized controlled trial comparing transdiagnostic metacognitive therapy and disorder-specific cognitive-behavioral therapy for anxiety disorders. The purpose of the study is to explore participant perceptions of the respective treatment models to facilitate implementation and dissemination of the treatments.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 years or older,
• A principal diagnosis of generalized anxiety disorder, social anxiety disorder, or posttraumatic stress disorder,
• No change in dose during the last six weeks if on pharmacological treatment, and
• Ability to read and speak Swedish.

Exclusion criteria

• A current diagnosis of psychotic disorder, bipolar disorder, neurocognitive disorder, or moderate to severe substance use disorder,
• Acute suicide risk, or
• Concurrent psychological treatment.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Transdiagnostic metacognitive therapy

Experimental group

Description:

Metacognitive therapy in a transdiagnostic format; a single treatment protocol is used for all three anxiety disorders

Treatment:

Behavioral: Transdiagnostic metacognitive therapy

Disorder-specific cognitive-behavioral therapy

Active Comparator group

Description:

Cognitive-behavioral therapy in a disorder-specific format; each of the three anxiety disorders is treated using a separate treatment protocol

Treatment:

Behavioral: Disorder-specific cognitive-behavioral therapy