Metacognitive Therapy for Patients With Obsessive-Compulsive Disorder

Philipps University

Status: Completed

Conditions: Obsessive-Compulsive Disorder

Treatments: Behavioral: Metacognitive Therapy; Behavioral: Exposure and Response Prevention

Study type: Interventional

Funder types: Other

Identifiers

NCT01483339

MCT_OCD_2011

Details and patient eligibility

About

Cognitive behavior therapy is the most effective treatment of obsessive-compulsive disorder. However, the majority of treated patients remain symptomatic. The metacognitive therapy by Wells (1997) could achieve substantial gains in first pilot studies. The purpose of this study is to investigate this approach with a randomized controlled trial by comparing metacognitive therapy with exposure and response prevention for obsessive-compulsive disorder.

Enrollment: 37 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary diagnosis: obsessive-compulsive disorder
• German-speaking
• Agreeing to participate, verified by completion of informed consent

Exclusion criteria

• Current or past diagnosis of substance dependence, psychosis, neurological conditions
• Mental retardation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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37 participants in 2 patient groups

Metacognitive Therapy

Experimental group

Treatment:

Behavioral: Metacognitive Therapy

Exposure and Response Prevention

Experimental group

Treatment:

Behavioral: Exposure and Response Prevention