Metacognitive Therapy Versus Cognitive Behavioral Therapy for Mixed Anxiety Disorders: A Randomized Controlled Trial.

Modum Bad

Status: Completed

Conditions: Mixed Anxiety Disorders

Treatments: Behavioral: Cognitive behavioral therapy; Behavioral: Metacognitive therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01889342

SveJoh 1

Details and patient eligibility

About

Comorbidity is normal in clinical practice. Metacognitive Therapy (MCT) is a transdiagnostic model and could therefore be well suited when it comes to treating patients with high rates of comorbidity. So far, no studies have examined MCT in comparison with the best documented and evidence based treatment, cognitive behavioral treatment(CBT), in a randomized controlled trial consisting of mixed anxiety disorder sample with high degree of comorbidity.

The main aim of this study is to 1) Evaluate the effectiveness of metacognitive therapy in a sample of mixed anxiety disorders as compared to a group receiving existing evidence-based single diagnosis CBT- treatment protocols 2) Investigate patterns and mechanisms of change in the two treatments.

Enrollment: 90 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• DSM IV diagnoses of SAD, PD/A or PTSD (CSR>4)
• Withdraw of all psychotropic medications before treatment

Exclusion criteria

• Psychosis
• Not willing to accept randomization
• Comorbid conditions are in immediate need of treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 2 patient groups

Metacognitive therapy

Experimental group

Description:

The treatment is based on the generic manual by Wells (2009).

Treatment:

Behavioral: Metacognitive therapy

Cognitive behavorial therapy

Active Comparator group

Description:

CBT includes the diagnose specific manuals for panic disorder (Clark, 1986), Social Phobia (Clark & Wells, 1995) and PTSD (Foa, 2007).

Treatment:

Behavioral: Cognitive behavioral therapy