Metal Ion Concentrations After Total Knee Arthroplasty

Mayo Clinic

Status: Active, not recruiting

Conditions: Blood Metal Ion Concentration; Arthroplasty, Replacement, Knee; Total Knee Replacement

Treatments: Other: Metal ion level testing

Study type: Observational

Funder types: Other

Identifiers

NCT06447922

24-004661

Details and patient eligibility

About

The purpose of this study is to analyze the metal ion concentrations in the patients blood following robotic-assisted total knee arthroplasty (TKA) compared to conventional total knee arthroplasty using cutting guides.

Full description

This study focuses on comparing metal ion levels in 50 inpatient participants undergoing primary total knee arthroplasty (TKA) with either conventional cutting guides or robotic assistance. Baseline blood examinations for Cobalt, Chromium, Titanium, and Nickel will be performed before TKA implantation at preoperative visits and on the first day following the procedure. The investigation will encompass patients receiving both conventional and robotic-assisted primary TKA, framed within a prospective cohort study design. Baseline characteristics and additional follow-up information will be gathered.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults undergoing conventional or robotic-assisted TKA
• Consent to the study

Exclusion criteria

• Patients who have undergone any previous arthroplasty procedures.
• Patients with metal implants, such as plates, nails, and screws, used in the repair of traumatic injuries.
• Patients below 110 pounds.

Trial design

60 participants in 2 patient groups

Conventional TKA with Cutting Guides

Description:

Patients undergoing a conventional total knee arthroplasty with cutting guides (no robot-assistance).

Treatment:

Other: Metal ion level testing

Robot-Assisted TKA

Description:

Patients undergoing a robot-assisted total knee arthroplasty.

Treatment:

Other: Metal ion level testing