Patterns of Care and Outcomes in METAstatic Soft Tissue SARComa (METASARC)

Institut Bergonié

Status: Completed

Conditions: Sarcoma; Chemotherapy; Metastases

Study type: Observational

Funder types: Other

Identifiers

NCT03977818

IB2017-METASARC

Details and patient eligibility

About

Well-designed observational studies of individuals with rare tumors are needed to improve patient care, clinical investigations, and the education of healthcare professionals.

The patterns of care, outcomes, and prognostic factors of a cohort of 2225 patients with metastatic soft tissue sarcomas who were diagnosed between 1990 and 2013 and documented in the prospectively maintained database of the French Sarcoma Group will be analyzed with a focus on : number/frequency of systemic treatments per patient, number/frequency of patients with locoregional treatment of the metastasis, number/frequency of patients with chemotherapy, number/frequency of patients with an off-label drug.

Outcome (time-to-next treatment [TNT] and overall survival [OS]) will be reported according to histological subtype, as well as the association between TNT and OS.

Prognostic factors of OS will be investigated.

Enrollment: 2,165 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• advanced soft tissue sarcoma
• age > 18

Exclusion criteria

-

Trial design

2,165 participants in 1 patient group

patients with metastatic softtissue sarcomas diagnosed between 1990 and 2013