Metformin Use and Vitamin B12 Deficiency

Northwell Health

Status: Completed

Conditions: Vitamin B12 Deficiency; Type 2 Diabetes Mellitus

Study type: Observational

Funder types: Other

Identifiers

NCT01136512

07040

Details and patient eligibility

About

The primary objective is to determine the incidence of Vitamin B12 deficiency in patients on metformin therapy for diabetes.

Enrollment: 89 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Age 20-80; diagnosed with type 2 diabetes for at least 30 days

Exclusion Criteria:known vitamin B12 or folate deficiency; pernicious anemia; on vitamin B12 therapy; hematological malignancy; methotrexate use; alcohol intake greater than two drinks per day; vegetarian diet; previous gastric surgery; inflammatory bowel disease

Trial design

89 participants in 2 patient groups

metformin use

Description:

Patients with type 2 diabetes treated with metformin

no metformin use

Description:

Patients with type 2 diabetes who are not being treated with metformin