Methods of Pancreatic Stump Closure for Distal Pancreatectomy

Naval Military Medical University

Status: Completed

Conditions: Pancreatectomy

Treatments: Procedure: simple closure with a closure device; Procedure: stapler combined with electrocautery

Study type: Interventional

Funder types: Other

Identifiers

NCT06424431

CHEC2024-110

Details and patient eligibility

About

The aim of this study is to conduct a retrospective analysis of patients who underwent distal pancreatectomy in our hospital, aiming to evaluate the safety and feasibility of two methods for closure of the pancreatic remnant: simple closure with a closure device and closure combined with electrocoagulation.

Full description

The aim of this study is to conduct a retrospective analysis of patients who underwent distal pancreatectomy in our hospital, aiming to evaluate the safety and feasibility of two methods for closure of the pancreatic remnant: simple closure with a closure device and closure combined with electrocoagulation. This study aims to determine which method is safer and more feasible, with the potential to reduce postoperative complications, improve outcomes, facilitate better patient recovery, and thereby provide better guidance for clinical practice.

Enrollment: 487 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who underwent distal pancreatectomy performed by Director Jin Gang's team at Changhai Hospital affiliated with Naval Medical University between January 2019 and January 2023.
• Patients who underwent closure of the pancreatic remnant using either simple closure or closure combined with electrocoagulation during surgery.

Exclusion criteria

• Patients undergoing surgeries by other primary clinical teams during the same period.
• Patients undergoing closure of the pancreatic remnant using methods other than those mentioned.
• Patients who violate the requirements of the study protocol.
• Patients with incomplete data collection in the hospital's diagnostic and treatment system.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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487 participants in 2 patient groups

Stapler

Other group

Description:

Simple closure with a closure device for closure of the pancreatic remnant in distal pancreatectomy.

Treatment:

Procedure: simple closure with a closure device

Stapler combined with electrocautery

Experimental group

Description:

Closure with a closure device combined with electrocoagulation for closure of the pancreatic remnant in distal pancreatectomy.

Treatment:

Procedure: stapler combined with electrocautery