Methods of Weight Loss in Overweight Coronary Patients

University of Vermont

Status and phase: Completed; Phase 3

Conditions: Obesity

Treatments: Behavioral: high caloric expenditure exercise; Behavioral: low caloric expenditure exercise plus dietary counseling

Study type: Interventional

Funder types: Other

Identifiers

NCT00628277

03-049

Details and patient eligibility

About

We hypothesize that a combination of high-caloric expenditure exercise and behavioral weight loss counseling would lead to a greater loss of fat mass and a greater improvement in cardiometabolic risk factors that standard (lower caloric expenditure) cardiac rehabilitation exercise plus counseling.

Full description

We hypothesize that a combination of high-caloric expenditure exercise and behavioral weight loss counseling would lead to a greater loss of fat mass and a greater improvement in cardiometabolic risk factors that standard (lower caloric expenditure) cardiac rehabilitation exercise plus counseling.

The study population consists of overweight (BMI >27) patients with established coronary heart disease. The exercise and counseling program was of 4 months duration with extended follow up at 1 year.

Enrollment: 74 patients

Sex: All

Ages: 21 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Coronary heart disease
• BMI > 27
• Peak Vo2 > 14.4 ml/kg/min

Exclusion criteria

• Presence of diabetes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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74 participants in 2 patient groups

1

Experimental group

Description:

Arm 1: high caloric expenditure exercise plus dietary counseling

Treatment:

Behavioral: high caloric expenditure exercise

2

Active Comparator group

Description:

Arm 2: low caloric expenditure exercise plus dietary counseling

Treatment:

Behavioral: low caloric expenditure exercise plus dietary counseling