Methotrexate Polyglutamate Measurements in Patients With Inflammatory Bowel Disease

Boston Children's Hospital

Status: Suspended

Conditions: IBD

Treatments: Diagnostic Test: MTX Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT04205734

IRB-P00028947

Details and patient eligibility

About

There are currently no serum levels to help guide appropriate methotrexate therapy. Data from this study will assess the correlation between dosing and whole blood methotrexate(MTX) polyglutamate measurements in children and adolescents with IBD.

Full description

This is a cross-sectional study design. Subjects will be requested to provide one blood sample to be collected during the conduct of their routine clinical care. Data related to the diagnosis and interval assessment of enrolled subjects will also be collected.

Enrollment: 100 estimated patients

Sex: All

Ages: 1 to 21 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• IBD
• Methotrexate Therapy

Exclusion criteria

• Inability to provide relevant samples