Methylated Biomarkers Predictive of Endometrial Cancer Risk (BioMEC)

University of Manchester

Status: Active, not recruiting

Conditions: Endometrial Cancer

Treatments: Procedure: Hysterectomy

Study type: Observational

Funder types: Other

Identifiers

NCT06800677

334940

Details and patient eligibility

About

The goal of this observational study is to identify endometrial cancer risk predictive biomarkers and to optimise the methodology for their detection and quantification in non-invasive samples.

Enrollment: 200 estimated patients

Sex: Female

Ages: 45 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Women aged 45-70 years
2. Attending St Mary's Hospital, Manchester for an elective hysterectomy by any route for either the treatment of endometrial cancer or a benign gynaecological condition
3. Able to consent to participation in the study

Exclusion criteria

1. Presence of malignancy asides from endometrial cancer
2. Undergoing elective hysterectomy for suspected ovarian cancer

Trial design

200 participants in 2 patient groups

Cases

Description:

Women diagnosed with endometrial cancer of any grade, stage and histological type

Treatment:

Procedure: Hysterectomy

Controls

Description:

Women undergoing a hysterectomy for benign indications

Treatment:

Procedure: Hysterectomy