Methylphenidate and Driving Ability in Adult Patients With Attention-Deficit Hyperactivity Disorder

Utrecht Institute for Pharmaceutical Sciences

Status and phase: Completed; Phase 4

Conditions: ADHD

Treatments: Drug: methylphenidate

Study type: Interventional

Funder types: Other

Identifiers

NCT00223561

02/021

Details and patient eligibility

About

The primary purpose of this study is to determine the effects of methylphenidate versus placebo on driving ability of adult ADHD patients.

Full description

This study was set-up to examine the controversial issue whether or not it is safe to drive a car or not when treated with methylphenidate.

On-the-road driving tests during normal traffic are conducted to determine the effects of methylphenidate versus placebo on driving ability of adult ADHD patients.In addition, two laboratory tests are conducted to examine memory functioning and inhibitory control.

Sex: All

Ages: 21 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult ADHD patient over 21 years old
• valid driver's license for at least 3 years
• treated with methylphenidate
• written informed consent

Exclusion criteria

• use of illicit drugs
• use of drugs or having medical conditions known to affect driving ability

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind