MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASE

Çukurova University

Status: Completed

Conditions: Behçet's Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01780363

CUTFBAP2501201138 (Other Identifier)

CUTFBAP25011138 (Other Identifier)

BH-MVK

Details and patient eligibility

About

Background: Genetics is suggested to play a critical role in the development of Behçet's disease (BD). Shared phenotypic features requires an approach to the differential diagnosis from periodic febrile syndromes particularly from mevalonate kinase deficiency related diseases. We planned to study for evaluating the frequency of mutations and their clinical significance in mevalonate kinase gene in Turkish patients with Behçet's disease.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Behçet patients

Exclusion criteria

• Diagnosis of periodic fever syndromes

Trial design

0 participants in 2 patient groups

controls

Description:

frequency of mevalonate kinase gene frequency

Behçet patients

Description:

frequency of mevalonate kinase gene mutations