Mi-RNA and COVID-19

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Enrolling

Conditions: COVID-19

Treatments: Diagnostic Test: mi-RNA analysis

Study type: Observational

Funder types: Other

Identifiers

NCT06881160

3155

Details and patient eligibility

About

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), induces a spectrum of clinical conditions ranging from asymptomatic infection to life threatening severe disease, characterized by respiratory failure, shock and multi-organ dysfunction requiring admission in the intensive care unit (ICU).

The aim of the present study is to analyze miRNAs associated with SARS-CoV-2 infection, disease severity and mortality.

Enrollment: 49 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years
• diagnosis of SARS-CoV-2 infection confirmed by molecular testing on nasopharyngeal swabs

Exclusion criteria

• pregnant women

Trial design

49 participants in 2 patient groups

Mild Respiratory Failure Covid-19

Description:

Patients with Covid-19 and mild respiratory failure defined as PaO2/FiO2 201-300 mm Hg

Treatment:

Diagnostic Test: mi-RNA analysis

Severe Respiratory Failure Covid-19

Description:

Patients with Covid-19 and severe respiratory failure defined as PaO2/FiO2 ≤100 mm Hg.

Treatment:

Diagnostic Test: mi-RNA analysis