Micro- and Macro-Circulation in Cardiac Surgery Patients (MiMaC)

San Donato Group (GSD)

Status: Suspended

Conditions: Cardiac Surgery; Coronary Artery Bypass Graft; Surgical Aortic Valve Replacement

Treatments: Diagnostic Test: Acquisition of cardiovascular signals and microcirculation sidestream darkfield images

Study type: Observational

Funder types: Other

Identifiers

NCT05706545

MiMaC

Details and patient eligibility

About

The hypothesis under the study is that there could be a link between a dysfunction in peripheral microcirculation, sublingual microcirculation or cardiovascular control and the development of post cardiac surgery major morbidities (stroke, acute kidney injury, prolonged intubation, mediastinitis, surgical reopening, death).

The state of sublingual microcirculation, of peripheral microcirculation and cardiovascular control will be assessed in 100 patients undergoing cardiac surgery during general anesthesia before the intervention and at the end of the intervention at the arrival in post-surgery ICU by means of signal processing techniques.

The extracted markers will be used to assess a statistical prediction model of major morbidities.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age >18 yrs
• indication for a cardiac surgery intervention
• spontaneous sinus rhythm
• informed consent

Exclusion criteria

• know autonomic nervous systems pathologies or dysfunctions
• pregnancy