Micro-Osteoperforations to Accelerate Maxillary Canine Retraction in Class I Malocclusion (MOPs)

Can Tho University of Medicine and Pharmacy

Status: Completed

Conditions: Malocclusion, Angle Class I

Treatments: Procedure: Micro-osteoperforations (MOPs); Procedure: Conventional Canine Retraction

Study type: Interventional

Funder types: Other

Identifiers

NCT07155018

IRB-164- (Registry Identifier)

DuongThaoTrangCtump

Details and patient eligibility

About

This single-blinded, split-mouth randomized controlled trial investigates whether micro-osteoperforations (MOPs) can accelerate maxillary canine retraction in orthodontic patients requiring bilateral premolar extraction. The study also evaluates postoperative pain levels using the Visual Analog Scale at 1, 3, and 7 days.

Full description

MOPs are a flapless, minimally invasive surgical technique that stimulates bone remodeling and may reduce orthodontic treatment time. In this trial, one side of each patient receives MOPs while the contralateral side serves as control. Canine retraction is performed using miniscrews, power arms, and NiTi coil springs. Outcomes include the rate of canine movement over 16 weeks and pain assessment using VAS.

Enrollment: 40 patients

Sex: All

Ages: 16 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 16-25 years
• Patients requiring bilateral extraction of maxillary first premolars as part of orthodontic treatment
• Angle Class I molar relationship
• No previous orthodontic treatment

Exclusion criteria

• History of craniofacial trauma or congenital anomalies
• Systemic or bone-related diseases
• Current smoking
• Use of medications affecting bone metabolism

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Experimental: Micro-osteoperforations

Experimental group

Description:

On the experimental side, micro-osteoperforations (MOPs) were performed distal to the maxillary canine under local anesthesia using the Excellerator RT device. Three perforations, each 1.5 mm in diameter and 5 mm deep, were created in the attached gingiva. Canine retraction was then carried out using miniscrew anchorage and NiTi closed-coil springs.

Treatment:

Procedure: Micro-osteoperforations (MOPs)

Control: Conventional Retraction

Active Comparator group

Description:

On the control side, maxillary canine retraction was performed using miniscrew anchorage and NiTi closed-coil springs without any micro-osteoperforations. The mechanics were identical to the experimental side to ensure comparability.

Treatment:

Procedure: Conventional Canine Retraction