Microalbuminuria Predicting CIAKI After CAG (MPCC)

Nanjing Medical University

Status: Unknown

Conditions: Contrast-induced Acute Kidney Injury; Microalbuminuria

Treatments: Other: microalbuminuria

Study type: Observational

Funder types: Other

Identifiers

NCT02808845

CIAKI-1

Details and patient eligibility

About

The purpose of this study is to investigate the association between pre-existing microalbuminuria and contrast-induced acute kidney injury (CIAKI) following coronary angiography (CAG).

Enrollment: 800 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with eGFR≥30ml/min and without macroalbuminuria undergoing CAG.

Exclusion criteria

• Pregnancy
• Lactation
• Allergic history of contrast media
• Having been received contrast media within 7 days
• Use of nephrotoxic medications within 7 days
• eGFR <30 ml/min, macroalbuminuria (ACR >300 mg/g)
• Renal transplantation, emergent coronary angiography
• Cardiogenic shock, pulmonary edema
• Use of intra-aortic balloon pump (IABP) or mechanical ventilation
• Multiple myeloma and other malignant tumor
• Life expectancy less than 12 months

Trial design

800 participants in 4 patient groups

microalbuminuria with eGFR≥60ml/min

Description:

microalbuminuria group with estimated glomerular filtration rate (eGFR) ≥60ml/min.

Treatment:

Other: microalbuminuria

normal-albuminuria group with eGFR≥60ml/min

Description:

normal-albuminuria group with estimated glomerular filtration rate (eGFR) ≥60ml/min.

microalbuminuria group with eGFR<60ml/min

Description:

microalbuminuria group with estimated glomerular filtration rate (eGFR) \<60ml/min.

Treatment:

Other: microalbuminuria

normal-albuminuria group with eGFR<60ml/min

Description:

normal-albuminuria group with estimated glomerular filtration rate (eGFR) \<60ml/min.