Microarray Analysis of microRNA Expression in Basal Cell Carcinoma

Ruhr University of Bochum

Status: Completed

Conditions: Basal Cell Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT01498250

microRNA6

Details and patient eligibility

About

Perturbations in microRNA (miRNA) expression profiles has been reported for a variety of cancers. This study will be an exploratory analysis of miRNA expression in basal cell carcinoma by miRNA expression profiling using microarrays.

Full description

Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC are included in the study to perform an exploratory analysis by miRNA expression profiling using microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time quantitative polymerase chain reaction (RT-PCR).

Enrollment: 7 patients

Sex: All

Ages: 1+ year old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Basal Cell Carcinoma

Exclusion criteria

• Other Skin Cancer than Basal Cell Carcinoma

Trial design

7 participants in 2 patient groups

basal cell carcinoma

non-lesional skin