Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine

Institute of Child Health

Status and phase: Completed; Phase 4

Conditions: Surgical Infants Requiring Total Parenteral Nutrition

Treatments: Dietary Supplement: Isonitrogenous Vaminolact; Drug: Dipeptiven (L-glutamine- Lalanine)

Study type: Interventional

Funder types: Other

Identifiers

NCT00647036

07SG10

Details and patient eligibility

About

We hypothesise that the addition of glutamine supplementation to both parenteral nutrition and enteral feeds in surgical newborn infants leads to a reduction in bacterial invasion.

Enrollment: 60 patients

Sex: All

Ages: Under 3 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infants who have undergone surgical procedures for congenital anomalies or
• Intestinal inflammation who require total parenteral nutrition.

Exclusion criteria

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

---

60 participants in 2 patient groups, including a placebo group

1

Active Comparator group

Description:

Dipeptiven (L-glutamine- Lalanine)

Treatment:

Drug: Dipeptiven (L-glutamine- Lalanine)

2

Placebo Comparator group

Description:

Isonitrogenous Vaminolact

Treatment:

Dietary Supplement: Isonitrogenous Vaminolact