Microbial Soy Milk Consumption, Inflammation and Renal Function Among Type 2 Diabetic Patients With Nephropathy

Isfahan University of Medical Sciences

Status: Completed

Conditions: Type II Diabetic Patients With Nephropathy

Treatments: Dietary Supplement: probiotic soy milk

Study type: Interventional

Funder types: Other

Identifiers

NCT02704884

394733

Details and patient eligibility

About

The aim of the present study was to determine the effects of fortified soy milk with L. planetarium A7 on a cytokine receptor, an adipokine and renal function biomarkers in type II diabetic patients with nephropathy.

Enrollment: 48 patients

Sex: All

Ages: 32 to 68 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults
• Type 2 diabetic patients with stages 1 and 2 of nephropathy (defined as meeting criteria including fasting blood glucose >126 mg/dL, hypoglycemic agents, or insulin intake, proteinuria >300 mg/day, and glomerular filtration rate >90 mL/min)

Exclusion criteria

• pregnancy or lactating in women
• allergy or intolerance to soy milk or avoidance of soy milk consumption
• smoking, alcoholism
• recent antibiotic therapy and using of supplements containing vitamins and minerals
• any medical condition such as inflammatory bowel disease, infection, liver disease and rheumatoid arthritis.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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48 participants in 2 patient groups

probiotic soy milk

Experimental group

Description:

consume a diet containing 200 ml/day probiotic soy milk in intervention group

Treatment:

Dietary Supplement: probiotic soy milk

soy milk

Active Comparator group

Description:

200 ml/day soy milk in the control condition

Treatment:

Dietary Supplement: probiotic soy milk