Microbiological Epidemiology in Patients Experiencing Microbiological or Clinical Failure Following Reimplantation After a 2-stage Exchange Strategy for Hip or Knee Prosthetic Joint Infection

Civil Hospices of Lyon

Status: Completed

Conditions: Bone and Joint Infection; EPIDEMIOLOGY; Bacterial Infections

Treatments: Other: failure after reimplantation

Study type: Observational

Funder types: Other

Identifiers

NCT03627000

17-089-2

Details and patient eligibility

About

This study concerns patients having had an infection on their prosthesis (hip, knee,..) and for whom a 2-step exchange of prosthesis has been done.

A 2-step exchange consists in explantation of the prosthesis and implementation of a spacer at the first stage, and reimplantation of a new prosthesis in a second stage. Patients with late prosthetic joint infection are at risk for superinfection at the time of reimplantation.

The aim is to determine the microbiological epidemiology in patients experiencing failure following reimplantation to establish, based on the drug susceptibilities, which cement could be the most active.

Enrollment: 114 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with prosthetic joint infection having had a 2-step exchange at least from the reimplantation, between 2013 and 2015.

Exclusion criteria

Trial design

114 participants in 1 patient group

failure after reimplantation

Description:

description of the failure at the reimplantation

Treatment:

Other: failure after reimplantation